发明名称 Mpr-related abc transporter encoding nucleic acids and methods of use thereof
摘要 Novel human MOAT genes and their encoded proteins are provided herein. The MRP-related ABC transporters encoded by the disclosed nucleic acid sequences play a pivotal role in the efflux of pharmacologically benefical reagents from tumor cells. MOAT genes and their encoded proteins provide valuable therapeutic targets for the design of anti-cancer agents which inhibit the aberrant growth of malignant cells.
申请公布号 AU3207799(A) 申请公布日期 1999.10.18
申请号 AU19990032077 申请日期 1999.03.26
申请人 FOX CHASE CANCER CENTER 发明人 GARY KRUH;KUN LEE;MARTIN BELINSKY;LISA BAIN
分类号 A61P35/00;C07K14/705;C12N15/12 主分类号 A61P35/00
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