发明名称 |
Mpr-related abc transporter encoding nucleic acids and methods of use thereof |
摘要 |
Novel human MOAT genes and their encoded proteins are provided herein. The MRP-related ABC transporters encoded by the disclosed nucleic acid sequences play a pivotal role in the efflux of pharmacologically benefical reagents from tumor cells. MOAT genes and their encoded proteins provide valuable therapeutic targets for the design of anti-cancer agents which inhibit the aberrant growth of malignant cells. |
申请公布号 |
AU3207799(A) |
申请公布日期 |
1999.10.18 |
申请号 |
AU19990032077 |
申请日期 |
1999.03.26 |
申请人 |
FOX CHASE CANCER CENTER |
发明人 |
GARY KRUH;KUN LEE;MARTIN BELINSKY;LISA BAIN |
分类号 |
A61P35/00;C07K14/705;C12N15/12 |
主分类号 |
A61P35/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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