| 摘要 |
<p>The present invention relates to a method of tissue regeneration of a wound or burn in a mammal. This method comprises covering the wound with a membrane comprising a biodegradable, fibrous lattice and an optional outer moisture barrier, wherein the lattice is seeded with cultured cells obtained from a culture grown to subconfluence. This allows infiltration of the grafted matrix by mesenchymal cells and blood vessels from healthy underlying tissue, forming a neodermis, and proliferation of the keratinocytes, forming a neoepidermis. The resulting graft has excellent take rates and has the appearance, growth, maturation and differentiation of normal tissue.</p> |
