| 发明名称 |
Use of isoxazole-amide or croton-amide derivatives to modulate apoptosis |
| 摘要 |
Use of compounds of formula (I) or (II) and their salts is claimed for the modulation of apoptosis. R1 = 1-4C alkyl, 3-5C cycloalkyl, 2-6C alkenyl or 2-6C alkynyl; R2 = CF3, OCF3, SCF3, OH, NO2, halo, benzyl, phenyl, CN or phenoxy (optionally substituted by 1-4C alkyl, halo, OCF3 or OCH3); R3 = 1-4C alkyl, halo or H; and X = CH or N.
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| 申请公布号 |
DE19640555(A1) |
申请公布日期 |
1998.04.02 |
| 申请号 |
DE19961040555 |
申请日期 |
1996.10.01 |
| 申请人 |
HOECHST AG, 65929 FRANKFURT, DE |
发明人 |
MUELLNER, STEFAN, DR., 65239 HOCHHEIM, DE;DAX, CLAUDIA, 64579 GERNSHEIM, DE |
| 分类号 |
A61K31/275;A61K31/42;A61K31/445;A61K38/13;A61K45/06;(IPC1-7):A61K31/44 |
主分类号 |
A61K31/275 |
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