发明名称 |
Compounds useful for inhibition of farnesyl protein transferase |
摘要 |
Novel compounds of formula (1.0) are disclosed. Compounds of formula (1.0) are represented by the compounds of formulas (1.4) or (1.5) wherein R<1>, R<3> and R<4> are each independently selected from halo. Also disclosed are methods of inhibiting farnesyl protein transferase and the growth of abnormal cells, such as tumor cells. |
申请公布号 |
AU5196698(A) |
申请公布日期 |
1998.04.02 |
申请号 |
AU19980051966 |
申请日期 |
1997.09.11 |
申请人 |
SCHERING CORPORATION |
发明人 |
ARTHUR G TAVERAS;ALAN K. MALLAMS;ADRIANO AFONSO;STACY W REMISZEWSKI;F. GEORGE NJOROGE;RONALD J DOLL;TARIK LALWANI;CARMEN ALVAREZ |
分类号 |
C07D401/04;A61K31/4545;A61K31/496;A61K31/513;A61K31/5377;A61P35/00;C07D401/12;C07D401/14;C07D405/14;C07D409/14;C07D413/14;C07D417/14;C07D471/04;C07D521/00 |
主分类号 |
C07D401/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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