| 发明名称 |
USE OF N-L-ALPHA-ASPARTYL-L-PHENYLALANINE 1-METHYL ESTER AND ITS DERIVATIVES IN DISEASE REGRESSION |
| 摘要 |
N-L-.alpha.-Aspartyl-L-phenylalanine 1-methyl ester (APM) and its derivatives have been found to effect disease regression in osteoarthritis, osteoporosis, and rheumatoid arthritis. APM performs as a TNF-.alpha. antagonist as well as an antipyretic agent.
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| 申请公布号 |
CA2266098(A1) |
申请公布日期 |
1998.04.02 |
| 申请号 |
CA19972266098 |
申请日期 |
1997.09.26 |
| 申请人 |
OKLAHOMA MEDICAL RESEARCH FOUNDATION |
发明人 |
EDMUNDSON, ALLEN B.;MANION, CARL V. |
| 分类号 |
A61K38/00;A61K38/05;A61P19/02;A61P19/10;A61P29/00;(IPC1-7):A61K38/05 |
主分类号 |
A61K38/00 |
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