发明名称 |
A process for the preparation of nepinalone |
摘要 |
<p>A process for the preparation of 1-methyl-1-[2-(1-N-piperidine)ethyl]-1,2,3,4-tetrahydronaphthalen-2-one hydrochloride (also named Nepinalone) which consists in reacting 2-phenylpropionic acid chloride with ethylene, obtaining 1-methyl-2-tetralone, which is subsequently reacted with 2-chloroethyl-1-N-piperidine, using heptane as the solvent; and subsequent salifying.</p> |
申请公布号 |
GR3025664(T3) |
申请公布日期 |
1998.03.31 |
申请号 |
GR19970403313T |
申请日期 |
1997.12.16 |
申请人 |
BIOINDUSTRIA FARMACEUTICI S.P.A. |
发明人 |
TENCONI, FRANCO;FURFARO, SILVANA |
分类号 |
C07D295/116;(IPC1-7):C07D295/10 |
主分类号 |
C07D295/116 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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