| 摘要 |
PCT No. PCT/EP94/01905 Sec. 371 Date Nov. 20, 1995 Sec. 102(e) Date Nov. 20, 1995 PCT Filed Jun. 8, 1994 PCT Pub. No. WO94/29328 PCT Pub. Date Dec. 22, 1994Antiparasitic compounds of the formula (I) between the 3-4 and 4-5 positions represent optional bonds and either (i) the 3-4 optional bond is present; the 4-5 optional bond is absent, R7 is absent and R6 is halogen atom, an isothiocyanate group, a diazo group, a thioureido group of formula NHCSNR15R16 where R15 and R16 are independently H, C1-C8 alkyl, cycloalkyl, aryl or aralkyl groups, an azido group or a C1-C8 alkylcarbonyl-thio group, or (ii) the 4-5 optional bond is present, the 3-4 optional bond is absent, R6 is absent and R7 is a mercapto, C1-C8 alkylthio, oxo, optionally substituted oximino or C1-C8 alkylcarbonylthio group; or R7 is absent and R6 is CN, with the provisos that the compounds where R6 is alpha -fluoro and R2 is CH(CH3)2, CH(CH3)C2H5, C(CH3)=CHCH3, C(CH3)=CHC2H5 and C(CH3)=CHCH(CH3)2 are excluded.
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