摘要 |
Compounds of formula (1) wherein X is either (a) a phenyl group optionally substituted by 1 or 2 substiuents each independently selected from halo, CF3, C1-C4 alkyl, C1-C4 alkoxy and hydroxy or (b) a thienyl group; and Y is of formula (Ya) or (Yb)where A and B are 0,1 or 2,D and E are 0 or 1,F is 0-3 and D + E + F = 1-3,Z is 0,1 or 2, R1 and R2 are H or alkyl or form a ring, and R3 is C1-C4 alkyl, C3-C6 cycloalkyl or optionally substituted phenyl or benzyl, are antimuscarinic bronchodilators useful for treating chronic obstructive airways disease or asthma.
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