发明名称 ANTIMUSCARINIC BRONCHODILATORS
摘要 Compounds of formula (1) wherein X is either (a) a phenyl group optionally substituted by 1 or 2 substiuents each independently selected from halo, CF3, C1-C4 alkyl, C1-C4 alkoxy and hydroxy or (b) a thienyl group; and Y is of formula (Ya) or (Yb)where A and B are 0,1 or 2,D and E are 0 or 1,F is 0-3 and D + E + F = 1-3,Z is 0,1 or 2, R1 and R2 are H or alkyl or form a ring, and R3 is C1-C4 alkyl, C3-C6 cycloalkyl or optionally substituted phenyl or benzyl, are antimuscarinic bronchodilators useful for treating chronic obstructive airways disease or asthma.
申请公布号 CA2116356(C) 申请公布日期 1998.03.31
申请号 CA19922116356 申请日期 1992.09.03
申请人 PFIZER INC. 发明人 CROSS, PETER E.;STOBIE, ALAN
分类号 A61K31/435;A61K31/00;A61K31/439;A61P11/00;A61P11/06;A61P11/08;A61P25/30;C07C317/44;C07C317/46;C07C323/56;C07D333/06;C07D333/24;C07D453/02;(IPC1-7):C07D453/02 主分类号 A61K31/435
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