摘要 |
An indole derivative of the formula: <CHEM> wherein R1 is lower alkoxy, lower alkoxycarbonyl-lower alkoxy, carboxy-lower alkoxy , lower alkoxycarbonyl, phenyl-lower alkoxy, lower alkyl being optionally substituted by hydroxy, di-lower alkylaminosulfonyl, etc., R2 is hydrogen, halogen, lower alkoxy, lower alkoxycarbonyl-lower alkoxy, carboxy-lower alkoxy, etc., R3 is hydrogen or lower alkyl, R4 is halogen or trifluoromethyl, R5 is lower alkyl, or a salt thereof, these compounds being potent beta 3-adrenergic receptor-stimulating agent with excellent adrenoceptor selectivity, and being useful in the prophylaxis or treatment of obesity or diabetes mellitus. |
申请人 |
DAINIPPON PHARMACEUTICAL CO. LTD. |
发明人 |
HARADA,HIROSHI;HIROKAWA,YOSHIMI;KATO,SHIRO;KAWASHIMA,HITOSHI;YOSHIDA,NAOYUKI |