| 发明名称 |
Salmonella virulence genes |
| 摘要 |
A vector capable of integrating into the chromosome of Salmonella including a first DNA sequence encoding a heterologous protein, a second DNA sequence encoding a marker, and a third DNA sequence encoding a phoP regulatory region regulated gene product necessary for virulence, the third DNA sequence being mutationally inactivated
|
| 申请公布号 |
US5731196(A) |
申请公布日期 |
1998.03.24 |
| 申请号 |
US19950476100 |
申请日期 |
1995.10.06 |
| 申请人 |
THE GENERAL HOSPITAL CORPORATION;PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
MILLER, III, SAMUEL I.;MEKALANOS, JOHN J. |
| 分类号 |
A61K39/00;A61K39/02;A61K39/112;A61P31/04;C07K14/255;C12N1/21;C12N15/01;C12N15/09;C12N15/74;C12Q1/68;C12R1/01;C12R1/42;(IPC1-7):C12N1/21;C12N15/31;C12N15/63 |
主分类号 |
A61K39/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
