发明名称 Substituted heteroalkyleneamine neurokinin antagonists
摘要 Compounds of formula I <IMAGE> (I) wherein Q1, Q2, Q3, and Q4 have any of the meanings given in the specification, their +E,uns N+EE -oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists of SP and NKA are useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.
申请公布号 US5731309(A) 申请公布日期 1998.03.24
申请号 US19950547515 申请日期 1995.10.24
申请人 ZENECA LIMITED 发明人 BERNSTEIN, PETER R.;MILLER, SCOTT C.
分类号 C07D211/52;A61K31/4427;A61K31/445;A61K31/4468;A61K31/451;A61K31/505;A61P9/08;A61P11/00;A61P11/08;A61P43/00;C07D211/58;C07D211/64;C07D211/76;C07D251/52;C07D401/04;(IPC1-7):C07D403/02;C07D401/02;A61K31/535;A61K31/54 主分类号 C07D211/52
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