| 摘要 |
There is disclosed a method of treating a mammal infected with a macrophage pathogen comprising administering an effective amount of a TGF- beta antagonist. Macrophage pathogens include any pathogenic microorganism that replicates within macrophage cell hosts as their exclusive or primary host cells. TGF- beta antagonists include blocking antibodies specific for a human TGF- beta , soluble TGF- beta receptors, protease inhibitors that inactivate a protease responsible for activating a precursor TGF- beta into an active, mature TGF- beta , and combinations thereof.
|
