发明名称 |
Therapeutic use of hypervariable region of monoclonal antibody M195 and constructs thereof |
摘要 |
Therapeutic agents and methods for treating and diagnosing acute or chronic leukemia are provided. Such agents comprises monoclonal antibody M195, or a chimeric antibody containing the hypervariable region of M195, conjugated to a cytotoxic agent, e.g. a radioisotope.
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申请公布号 |
US5730982(A) |
申请公布日期 |
1998.03.24 |
申请号 |
US19950383615 |
申请日期 |
1995.02.02 |
申请人 |
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH |
发明人 |
SCHEINBERG, DAVID A. |
分类号 |
A61K39/395;A61K38/00;A61K47/48;A61K48/00;A61K51/00;A61K51/10;C07K16/00;C07K16/28;C07K16/30;C07K19/00;C12N5/10;C12N15/02;C12N15/09;C12P21/08;C12R1/91;G01N33/53;G01N33/577;(IPC1-7):A61K39/395 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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