| 摘要 |
FIELD: medicine. SUBSTANCE: 3-substituted 1-carba-(1-detia)-cephemes have formula I <EMI ID=0.134 HE=36 WI=72 TI=CHI> where R is (C<SB>1</SB>-C<SB>6</SB>) alkyl or (C<SB>1</SB>-C<SB>6</SB>) halogen alkyl; A and <EMI ID=0.135 HE=3 WI=3 TI=CHI> are independently hydrogen atom, (C<SB>1</SB>-C<SB>6</SB>) alkyl, nitro, amino, pyridyl, or phenyl, or A and <EMI ID=0.136 HE=3 WI=3 TI=CHI> form together groups in which X is hydrogen, halogen, (C<SB>1</SB>-C<SB>6</SB>) alkoxy, amino, nitro groups and Y is nitrogen atom or carbon atom. EFFECT: improved quality. 8 cl
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