DISEASE ASSOCIATED MEMBRANE PROTEIN (DAMP)

摘要

The present invention provides a polynucleotide which identifies and encodes a novel human disease associated membrane protein (DAMP) and DAMP itself. The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding DAMP. The invention also provides pharmaceutical compositions containing DAMP and the use of such compositions for the treatment of cancer. The invention also provides diagnostic assays which utilize the polynucleotide to hybridize with the transcripts encoding DAMP or anti-DAMP antibodies which specifically bind to DAMP.