| 发明名称 |
METHOD OF INHIBITING BIOSYNTHESIS OF EIf5A |
| 摘要 |
A method and pharmaceutical composition for inhibiting or preventing the intracellular biosynthesis of EIf5A by the administration to a human or non-human mammal in need thereof an amount of a polyamine analogue or salt thereof sufficient to deplete the supply of intracellular spermidine required for EIf5A biosynthesis.
|
| 申请公布号 |
WO9810766(A1) |
申请公布日期 |
1998.03.19 |
| 申请号 |
WO1997US15909 |
申请日期 |
1997.09.12 |
| 申请人 |
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. |
发明人 |
BERGERON, RAYMOND, J., JR. |
| 分类号 |
C07D239/04;A61K31/00;A61K31/13;A61K31/131;A61K31/132;A61K31/133;A61K31/135;A61K31/136;A61K31/137;A61K31/505;A61K31/506;A61K31/785;A61P31/18;A61P43/00;(IPC1-7):A61K31/505 |
主分类号 |
C07D239/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
