摘要 |
<p>The present invention provides compounds of formula (I) wherein each R20, which may be the same of different, is a hydrogen or halogen; R' is methyl, hydrogen or R; R is a group of formula (II) wherein Z is a single or a double bond; n is 1-3; R1 is hydroxy, hydroxymethyl, amino, N-((C1-C5)alkyl)amino, aminomethyl, N-((C1-C5)alkyl)aminomethyl, N,N-di((C1-C5)alkyl)aminomethyl, (C1-C5)acyloxy or N-((C1-C5)acyl)amino, and R2 and R3 are hydrogen and, when Z is a single bond, R4 and R5, which may be the same or different, are each hydrogen or hydroxy; and pharmaceutically acceptable salts thereof; and the use of such compounds in medical therapy.</p> |