The present invention relates to a novel CK-4 protein which is a member of the CXC chemokine family. In particular, isolated nucleic acid molecules are provided encoding the human CK-4 protein. CK-4 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of CK-4 activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders.
申请公布号
WO9811138(A1)
申请公布日期
1998.03.19
申请号
WO1997US16144
申请日期
1997.09.11
申请人
HUMAN GENOME SCIENCES, INC.;OLSEN, HENRIK, S.;RUBEN, STEVEN, M.;ZENG, ZHI-ZHEN