| 摘要 |
<p>The present invention provides a method of preparing thienoÄ3,2-cÜpyridine derivatives of formula I: <CHEM> wherein R1 is selected from the group consisting of lower alkyl; lower alkylene phenyl; substituted lower alkylene phenyl wherein the phenyl is substituted from 1 to 3 times with lower alkyl, lower alkoxy, lower acyloxy, hydroxy, nitro and halo; lower alkylene naphthyl, lower alkylene thienyl; lower alkylene diphenyl; lower alkylene-hydroxy-phenyl; substituted lower alkylene-hydroxy-phenyl wherein the phenyl is substituted from 1 to 3 times with lower alkyl, lower alkoxy, lower acyloxy, hydroxy, nitro, and halo; lower alkylene-hydroxy-naphthyl; lower alkylene-hydroxy-thienyl; lower alkylene-hydroxy-diphenyl, and R2 is H or lower alkylene. The method comprises reacting a compound of a formula II: <CHEM> with a cyclic dioxy or cyclic dithio in the presence of catalyst.</p> |
