摘要 |
<p>The present invention relates to a subcutaneous delivery system comprising a biodegradable polymeric matrix and at least one of the pharmacologically active substances of general formula (I): wherein A represents an amino group -NH2 or an ammonium group -NH3<+> or a residue of general formula (II): wherein each of X1 to X5 represents, independently, an hydrogen atom, a linear or branched C1 to C6 alkyl group, a linear or branched C1 to C6 alkyloxy group, a hydroxyl group -OH, an amino group -NH2, a primary or secondary C1 to C6 alkylamino group, a halogen atom, a nitro group -NO2; said substance being embedded into said matrix. It relates also to a process for its preparation and to its use for the preparation of a medicament.</p> |
申请人 |
DEBIO RECHERCHE PHARMACEUTIQUE S.A.;MAUVERNAY, ROLLAND-YVES;PORCHET, HERVE;SCALFARO, PIETRO;HEIMGARTNER, FREDERIC;DUCREY, BERTRAND;PFEFFERLE, FRANCOIS;CAPANCIONI, SERGIO;MC CORMICK, MARK |
发明人 |
MAUVERNAY, ROLLAND-YVES;PORCHET, HERVE;SCALFARO, PIETRO;HEIMGARTNER, FREDERIC;DUCREY, BERTRAND;PFEFFERLE, FRANCOIS;CAPANCIONI, SERGIO;MC CORMICK, MARK |