发明名称 CHROMATOGRAPHY ADSORBENTS UTILIZING MERCAPTO HETEROCYCLIC LIGANDS
摘要 A pseudobioaffinity chromatography adsorbent adapted for use in selectively adsorbing immunoglobulins. In one embodiment, the adsorbent includes: (a) a solid support material; and (b) a ligand immobilized on the surface of the solid support material, said ligand being a compound of the formulawherein Y1 is selected from the group consisting of S, SCH3+, O, NH, NCH3, CH2 and CR1R2 wherein at least one of R1 and R2 is not hydrogen; wherein each of Y2, Y3 and Y4 is selected from the group consisting of N, NCH3+, CH, and CR wherein R is not hydrogen; and wherein at least two of Y1, Y2, Y3 and Y4 are neither CH2, CH, CR nor CR1R2.
申请公布号 EP0764048(A4) 申请公布日期 1998.03.18
申请号 EP19950919182 申请日期 1995.05.16
申请人 BIOSEPRA INC. 发明人 SCHWARZ, ALEXANDER;WILCHEK, MEIR
分类号 B01J20/281;A61K39/395;B01J20/32;C07K1/22;C07K16/00;C07K16/06;G01N30/88;(IPC1-7):B01J20/22;C07K1/16 主分类号 B01J20/281
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