Use of at least one pyrimidine derivative substituted in position G as stimulant of tyrosinase

摘要

Use of 6-substituted pyrimidin-3-oxide(s) of formula (I) in cosmetic or pharmaceutical compositions is new: R1, R2 = H or 1-12C alkyl; R3, R4 = 1-12C alkyl; or NR3R4 = heterocyclyl; provided that when NR3R4 forms piperidino, then ≥ 1 of R1 or R2 is not H. In an example a dermal cream contained the following: (Ia) 1 g; Ceteareth 30 7 g; glyceryl stearate 2 g; cetyl alcohol 1.5 g; polydimethylsiloxane 1.5 g; liquid paraffin 15 g; glycerine 20 g; preservatives and water to 100 g.