发明名称 |
SYNTHESIS AND IMMUNOGENICITY OF ROTAVIRUS GENES USING BACULOVIRUS EXPRESSION SYSTEM |
摘要 |
A method to express rotavirus genes in a baculovirus system. Different clones are used to express rotavirus genes for all of the viral proteins. These proteins are isolated in their native conformation. Some of these proteins show antigenic properties and are used to vaccinate human, agricultural animals and pet animals against diarrheal disease. The antigenic proteins are also used to detect the presence of the viral infectious agent either by themselves or in conjunction with antibodies produced against the antigenic proteins.
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申请公布号 |
CA1339732(C) |
申请公布日期 |
1998.03.17 |
申请号 |
CA19870554887 |
申请日期 |
1987.12.18 |
申请人 |
BAYLOR COLLEGE OF MEDICINE |
发明人 |
ESTES, MARY K. |
分类号 |
G01N33/569;A61K39/00;A61K39/15;C07K14/14;C12N7/00;C12N7/01;C12N7/04;C12N15/00;C12N15/09;C12N15/46;C12N15/866;C12P21/00;C12Q1/00;C12Q1/70;C12R1/91;G01N33/577;(IPC1-7):C12N15/33;A61K39/12;A61K39/42;C12N15/86 |
主分类号 |
G01N33/569 |
代理机构 |
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