| 摘要 |
<p>Benzopyranone Compounds having the following structure: (I) wherein R1, R2, X, Y and n are as defined herein, are disclosed. The Benzopyranone Compounds are useful for treating or preventing a bone-resorbing disease, a neoplastic disease, arthritis, a disease exacerbated by the presence of estrogen or a disease improved by the presence of estrogen, comprising administering an effective amount of a Benzopyranone Compound to a patient in need of the treating or preventing; activating the function of estrogen receptor ("ER") in a bone cell; inhibiting the function of ER in a cancer cell; inhibiting the expression of interleukin-6 ("IL-6") in a cell; and inhibiting the growth of a neoplastic cell, comprising contacting the cell with an effective amount of a Benzopyranone Compound.</p> |
