Sulfonamide compounds of azolones anti-helicobacter agents

摘要

PCT No. PCT/EP95/02619 Sec. 371 Date Jan. 9, 1997 Sec. 102(e) Date Jan. 9, 1997 PCT Filed Jul. 5, 1995 PCT Pub. No. WO96/01818 PCT Pub. Date Jan. 25, 1996The invention is concerned with the compounds having the formula <IMAGE> (I) <IMAGE> the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein Y is CH or N; R1, R2 and R3 each independently are hydrogen or C1-4alkyl; R4 and R5 each independently are hydrogen, halo, C1-4alkyl, C1-4alkyloxy, hydroxy, trifluoromethyl, trifluoromethyloxy or difluoromethyloxy; R6 is C1-4alkyl; or phenyl optionally substituted with halo, C1-4alkylcarbonylamino, C1-4alkyloxy, C1-4alkyl or nitro; Z is C=O or CHOH; and <IMAGE> is a radical of formula <IMAGE> (a-1) <IMAGE> (a-2) <IMAGE> (a-3) <IMAGE> (a-4) <IMAGE> (a-5) <IMAGE> (a-6) <IMAGE> (a-7) Compositions comprising said compounds, processes for preparing the same and the use of these compounds as a medicine.