摘要 |
A biocompatible, biodegradable composition for encouraging controlled growth, regeneration or repair of biological tissue or cells, the composition comprising a scaffold, formed from biodegradable and biocompatible material, and a receptor for a growth factor, or a growth factor-binding fragment or homologue thereof, located at or adjacent a surface of the scaffold. The tissue or cells are preferably neuronal, in which case the receptor is preferably a tyrosine receptor kinase (Trk), or a neurotrophin-binding fragment or homologue thereof. Such a composition may include one or more types of neurotrophin bound to the Trk or fragment or homologue thereof.
|