| 摘要 |
A method is disclosed for preparing and purifying N-[N-(3,3-dimethylbutyl)-L- alpha -aspartyl]-L-phenylalanine 1-methyl ester from aspartame and 3,3-dimethylbutyraldehyde by hydrogenation in an organic solvent solution followed by the formation of an aqueous/organic solvent solution having an organic solvent content of about 17% to about 30% by weight of the aqueous/organic solvent solution.
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