| 摘要 |
N-Benzylazolium derivatives of the general formula (I), wherein Q is the remainder of an azole compound of the formula II possessing antifungal activity; Z is nitrogen or methine; R1 and R2 are each independently a hydrogen atom or a group -OY [in which Y is a group easily hydrolyzable under physiological condition]; R3 and R4 are each independently a hydrogen or halogen atom, lower alkyl, lower alkoxy, lower alkylthio, (lower alkylcarbonyl)thiomethyl, carboxy or methoxycarbonyl; and X- is a pharmaceutically acceptable anion, as well as salts, hydrates or solvates of the compounds of the general formula (I) have antiftngal properties. |
