| 发明名称 |
AMIDE- OR CARBAMIDE DERIVATIVES HAVING ANTIHYPERCHOLESTEROL ACTIVITY, THEIR PRODUCTION AND THERAPEUTICAL USAGE |
| 摘要 |
FIELD: medicine, organic chemistry. SUBSTANCE: compounds having formula (I) <EMI ID=0.47 HE=30 WI=57 TI=CHI> where R is alkyl group, or groups having formula (II) <EMI ID=0.48 HE=27 WI=27 TI=CHI>, (III) <EMI ID=0.49 HE=21 WI=33 TI=CHI>, (IV) <EMI ID=0.50 HE=33 WI=33 TI=CHI> or (V) <EMI ID=0.51 HE=15 WI=33 TI=CHI> and R<SP>2</SP>, R<SP>3</SP>, R and R is hydrogen or various organic groups and their pharmaceutically acceptable salts are proposed for treatment and prophylaxis of hypercholesterolemia and atherosclerosis. EFFECT: improved quality of desired product. 33 cl, 32 dwg, 12 tbl
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| 申请公布号 |
RU2106340(C1) |
申请公布日期 |
1998.03.10 |
| 申请号 |
RU19940022743 |
申请日期 |
1994.06.29 |
| 申请人 |
SANKIO KOMPANI LIMITED |
发明人 |
AKIRA ESIDA;KOZO ODA;SADAO ISIKHARA;TAKASI KASAJ;FUDZIO SAJTO;KHIROJUKI KOJKE;TEJITIRO KOGA;EJITI KITAZAVA;KHIROSI KOGEN;ITIRO KHAJAKAVA;AKIRA ESIDA;KOZO ODA;SADAO ISIKHARA;TAKASI KASAJ;FUDZIO SAJTO;KHIROJUKI KOJKE;TEJITIRO KOGA;EJITI KITAZAVA;KHIROSI KOGEN;ITIRO KHAJAKAVA |
| 分类号 |
A61K31/165;A61K31/00;A61K31/16;A61K31/167;A61K31/17;A61K31/215;A61K31/235;A61K31/265;A61K31/335;A61K31/35;A61K31/352;A61K31/41;A61K31/415;A61K31/535;A61P3/06;A61P9/10;A61P43/00;C07C233/07;C07C233/11;C07C233/25;C07C233/26;C07C235/38;C07C235/48;C07C237/06;C07C237/40;C07C275/18;C07C275/28;C07C275/34;C07C323/39;C07D233/12;C07D233/56;C07D233/58;C07D233/60;C07D235/08;C07D235/12;C07D311/82;C07D311/90;C07D313/12;C07D405/12;C07D413/12;C07D521/00;C07F9/09;C12N9/99;(IPC1-7):C07C275/18 |
主分类号 |
A61K31/165 |
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