发明名称 |
Process for preparing 2-(10,11-dihydro-10-oxodibenzo{b,f}thiepin-2-yl)propionic acid and intermediates therefor |
摘要 |
A process for preparation of 2-(10,11-dihydro-10-oxodibenzoÄb,fÜthiepin-2-yl)propionic acid (i.e., Zaltoprofen) is performed by subjecting 2-(4-amino-3-carboxymethylphenyl)propionic acid or its salt to diazotization and subsequent reaction with thiophenol to produce 2-(3-carboxymethyl-4-phenylthiophenyl)propionic acid or its salt, and subjecting the product to cyclization reaction. Other related processes and related compounds are also disclosed. |
申请公布号 |
AU3952497(A) |
申请公布日期 |
1998.03.06 |
申请号 |
AU19970039524 |
申请日期 |
1997.08.22 |
申请人 |
NIPPON CHEMIPHAR CO. LTD.;UBE INDUSTRIES, LTD. |
发明人 |
MASAO YAMAMOTO;KUNIO KOBAYASHI;KATSUMASA HARADA;SHIGEYOSHI NISHINO;HIROSHI SASAKI |
分类号 |
C07D337/14;C07C205/56;C07C229/40;C07C323/62 |
主分类号 |
C07D337/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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