发明名称 |
Highly lipophilic camptothecin derivatives |
摘要 |
<p>Novel compounds, formulations and methods of treating patients with cancer are provided for in this invention. The compounds are derivatives of camptothecin, and specifically relate to compounds having novel substitutions at the C-7 position of the camptothecin scaffold B-ring. The formula I compounds are highly lipophilic, lactone stable, do not require metabolic activation, and are potent antineoplastic compounds.</p> |
申请公布号 |
AU4020497(A) |
申请公布日期 |
1998.03.06 |
申请号 |
AU19970040204 |
申请日期 |
1997.08.15 |
申请人 |
BIONUMERIK PHARMACEUTICALS, INC.;BRIAN RONALD LUCAS |
发明人 |
FREDERICK HERMAN HAUSHEER;KOCHAT HARIDAS;PEDDAIAHGARI SEETHARAMULU;DHANABALAN MURALI;DASHARATHA GAURAVARAM REDDY;SHIJIE YAO;PAVANKUMAR PETLURU |
分类号 |
A61K31/4745;A61P35/00;C07D491/22;C07D515/00;C07F7/10;(IPC1-7):C07D491/22;A61K31/47 |
主分类号 |
A61K31/4745 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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