摘要 |
Methods and apparatus for delivery of ultrasound to the brain, without requiring removal of portions of the skull, call for transmission of ultrasound with a plurality of transducers (12) aimed to induce cavitation at least at a selected region of the brain. An excitation source (22) is arranged for driving at least selected transducers at differing phases with respect to one another, e.g., to compensate for phase shifts (or phase distortions) effected by the skull on the ultrasound output by each transducer. As a result, the ultrasound waves reaching the selected region from the transducers arrive substantially in phase with one another, e.g., within 90 degrees and preferably 45 degrees, and still more preferably 20 degrees of one another. |