发明名称 |
4-(cykloalkyl)piperidin og 4-(cykloalkylalkyl)piperidin derivater, deres fremstilling og terapeutiske anvendelse |
摘要 |
<p>Compounds of general formula (I) are described, wherein Ar is (a) a phenyl group substituted with a halogen atom or (b) a group of general formula (I'), wherein X is a group of formula -CH2-, -(CH2)2- or -(CH2)3- and Z is a hydrogen or halogen atom or a methyl group, Y is a group of formula -CH2-, -CO- or -CHOH-, R1 is a hydrogen atom or a methyl group, R2 is a C3-C7 cycloalkyl group, and n is 0, 1, 2 or 3. Said compounds are useful in therapeutical applications as neurotrophic and neuroprotective agents.</p> |
申请公布号 |
NO981000(D0) |
申请公布日期 |
1998.03.06 |
申请号 |
NO19980001000 |
申请日期 |
1998.03.06 |
申请人 |
SYNTHELABO |
发明人 |
LARDENOIS, PATRICK;FROST, JONATHAN;PASAU, PATRICK;GEORGE, PASCAL;RENONES, MARIA-CARMEN;BARTSCH, REGINE;LI, WAI-TAK;MAGAT, PASCALE;DUPONT, REGIS |
分类号 |
C07D211/14;A61K31/00;A61K31/4427;A61K31/445;A61K31/4465;A61K31/4523;A61K31/454;A61K31/47;A61K31/472;A61K31/4725;A61K31/625;A61P25/00;A61P25/02;C07D211/12;C07D401/06;(IPC1-7):C07D |
主分类号 |
C07D211/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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