The use of hyaluronidase in the manufacturing of a drug for the treatment of conditions of interstitial edema in connection with organ grafting associated with an increased local content of hyaluronan in the connective tissue of a mammal. The drug comprises hyaluronidase in an amount giving a daily dosage of from 1 to 100,000 IU/kg body weight when given locally or systemically to a mammal. A method of treating conditions of interstitial edema in connection with organ grafting associated with an increased local synthesis of hyaluronan by systemic or local treatment with a pharmaceutical comprising hyaluronidase.
申请公布号
CA2262637(A1)
申请公布日期
1998.03.05
申请号
CA19972262637
申请日期
1997.07.24
申请人
WAHLBERG, JAN;JOHNSSON, CECILIA;HAELLGREN, ROGER;TUFVESON, GUNNAR
发明人
WAHLBERG, JAN;JOHNSSON, CECILIA;HAELLGREN, ROGER;TUFVESON, GUNNAR