PREVENTIVES OR REMEDIES FOR DISEASES INDUCED BY HYPOFUNCTION OF NITRIC OXIDE SYNTHASE (NOS)

摘要

Remedies containing as the active ingredient compounds represented by general formula (I) or pharmaceutically acceptable salts thereof, whereby diseases induced by the hypofunction of NOS can be efficaciously prevented or ameliorated, wherein R<1> and R<2> represent each hydrogen, or R<1> and R<2> form together a single bond; and R<3> represents -CH(OH)CH(OH)CH3, CH(OCOCH3)CH(OCOCH3)CH3, -CH3, -CH2OH or phenyl when R<1> and R<2> are hydrogen, or R<3> represents -COCH(OH)CH3 when R<1> and R<2> form together a single bond.