发明名称 Biomolecule attachment
摘要 <p>A method for making a medical device having a glycoprotein immobilized on a substrate surface is provided. The method comprises the steps of: (a) oxidizing 1,2-dihydroxy moieties with a periodate to form an aldehyde-functional material; (b) combining the aldehyde-functional material with an amino-functional material to bond the two materials together through an imine moiety; and (c) reacting the imine moiety with a reducing agent to form a secondary amine.</p>
申请公布号 EP0826382(A2) 申请公布日期 1998.03.04
申请号 EP19970306034 申请日期 1997.08.08
申请人 MEDTRONIC, INC. 发明人 KEOGH, JAMES R.
分类号 A61L27/28;A61L27/34;A61L29/08;A61L31/08;A61L31/10;A61L33/00;C07K14/00;C08J7/00;(IPC1-7):A61L33/00 主分类号 A61L27/28
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