| 摘要 |
PROBLEM TO BE SOLVED: To provide a method for producing 2,4,5-trifluoro-3-iodobenzoic acid useful as a raw material for the production of 2,4,5-trifluoro-3- trifluoromethylbenzoic acid which is an important intermediate for synthesizing quinolone carboxylic acid compounds useful as medicines, antibacterial agents and antiviral agents. SOLUTION: A method for producing 2,3,4-trifluoro-3-iodobenzoic acid comprises reacting 3-amino-2,4,5-trifluorobenzoic acid with hydroiodic acid in the presence of sodium nitrite and a cuprous halide in a solvent. |
