SCREENING METHOD OF NESFATIN-1-ACTION REGULATING SUBSTANCE OR NESFATIN-1-LIKE ACTION SUBSTANCE WITH THE USE OF RECEPTOR PROTEIN SELECTED FROM THE GROUP CONSISTING OF GPR3, GPR6 AND GPR12

摘要

An object of the present invention is to identify a Nesfatin-1 receptor, and to provide a method for screening or designing a Nesfatin-1-action regulating substance or a Nesfatin-1-like action substance using the Nesfatin-1 receptor. A method for screening a Nesfatin-1-like action substance comprising steps of making a test substance act on a receptor protein selected from the group consisting of GPR3, GPR6 and GPR12, and of identifying the Nesfatin-1-like action substance based on a change of Nesfatin-1 action.