发明名称 |
ACYLATED INSULIN ANALOGS |
摘要 |
The present invention relates to the field of diabetes. More particularly, the invention relates to a monomeric insulin analog wherein the A chain is the naturally occurring sequence of the human insulin A chain and the B chain is modified at either position B28 and B29 or both. The analog is mono-acylated at the N-terminal of the A chain or B chain or at the lysine. The acylated insulin analogs have an extended duration of action. |
申请公布号 |
HUT77030(A) |
申请公布日期 |
1998.03.02 |
申请号 |
HU19970001890 |
申请日期 |
1995.11.14 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
BAKER,JEFFREY CLAYTON;HANQUIER,JOSE MICHAEL |
分类号 |
C12N15/09;A61K38/00;A61K38/28;A61P3/08;A61P5/38;C07K14/62;G01N33/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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