| 发明名称 |
A CELLULAR PERTUSSIS VACCINES AND METHODS OF PREPARATION THEREOF. |
| 摘要 |
<p>Acellular pertussis vaccines comprise purified toxin or toxoid thereof, filamentous haemagglutinin, pertactin and fimbrial agglutinogens formulated to confer protection to at least 70 percent of members of an at-risk population. The fimbrial agglutinogens may be prepared from a Bordetella strain, particularly a B. pertussis strain, by a multiple step procedure involving extraction of the fimbrial agglutinogens from cell paste and concentrating and purifying the extracted material.</p> |
| 申请公布号 |
MX9708481(A) |
申请公布日期 |
1998.02.28 |
| 申请号 |
MX19970008481 |
申请日期 |
1996.05.02 |
| 申请人 |
CONNAUGHT LABORATORIES LIMITED |
发明人 |
JOHN R. VOSE;RAAFAT E.F. FAHIM;GAIL E.D. JACKSON;LARRY U. L. TAN;ANDREW HERBERT;LESLIE BOUX;LUIS BARRETO;JOHN THIPPHAWONG;MICHEL H. KLEIN |
| 分类号 |
A61K39/00;A61K39/10;A61K39/116;A61K39/155;A61P31/04;A61P37/00;C07K14/235;(IPC1-7):A61K39/10 |
主分类号 |
A61K39/00 |
| 代理机构 |
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代理人 |
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