发明名称 |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF GLOMERULONEPHRITIS AND OTHER INFLAMMATORY DISEASES. |
摘要 |
<p>The use of anti-C5 antibodies, e.g., monoclonal antibodies, to treat glomerulonephritis (GN) is disclosed. The administration of such antibodies at low dosage levels has been found to significantly reduce glomerular inflammation/enlargement and other pathologic conditions associated with GN. Also disclosed are novel anti-C5 antibodies and anti-C5 antibody-encoding nucleic acid molecules. These antibodies are useful in the treatment of GN and other inflammatory conditions involving pathologic activation of the complement system.</p> |
申请公布号 |
MX9605330(A) |
申请公布日期 |
1998.02.28 |
申请号 |
MX19960005330 |
申请日期 |
1995.05.01 |
申请人 |
ALEXION PHARMACEUTICALS, INC. |
发明人 |
MARK J. EVANS;LOUIS MATIS;ELLIOTT EILEEN MUELLER;STEVEN H. NYE |
分类号 |
(IPC1-7):A61K39/00;C07K16/46;C07K16/36;C07K16/18;C07K16/00;C07K14/75;C07K14/00;A61K39/395 |
主分类号 |
(IPC1-7):A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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