COLLAGEN FROM CELL CULTURES.

摘要

This invention is directed to a method for producing collagens from a collagen-producing cell in a cell culturing system. This invention is also directed to the collagens synthesized in vitro from the cell cultures. Collagen producing cells are cultured in the presence of an agent to inhibit or interfere with collagen crosslinking. The synthesized collagens are removed from the culture with a solution that maintains the viability of the cells in culture so that collagen synthesis and removal is repeated. The figure illustrates the repeated removal. The collagens produced by this method are useful for biomedical, biotechnology and cosmetic applications.