发明名称 ALKENYL-CARBOXYLIC ACID GUANIDINES SUBSTITUTED WITH PHENYL, PROCESSS FOR THEIR PREPARATION, THEIR UTILIZATION AS MEDICAMENT OR DIAGNOSIS AGENT, AS WELL AS A MEDICAMENT CONTAINING THEM.
摘要 The invention describes compounds of formula I: wherein T is equal to a and R(A), R(B), R(C), R(D), R(E), R(F), x and y with the meanings indicated on claims, as well as their pharmaceutically compatible salts, they are cell anti-portage efficient inhibitors between sodium and protons (Na+ and H+ interchanger). Therefore, they are appropriate in an outstanding manner for treatment of diseases which are to be attributed to an increased interchange between Na+ and H+.
申请公布号 MX9706380(A) 申请公布日期 1998.02.28
申请号 MX19970006380 申请日期 1997.08.21
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 JAN-ROBERT SCHWARK;JOACHIM BRENDEL;HEINZ-WERNER KLEEMANN;HANS JOCHEN LANG;ANDREAS WEICHERT;HANS-WILLI JANSEN;WOLFGANG SCHOLZ
分类号 C07D213/65;A01N1/00;A61K31/155;A61K31/165;A61K31/44;A61K31/4406;A61P3/06;A61P9/00;A61P9/06;A61P9/10;A61P13/02;A61P15/00;A61P25/00;A61P43/00;C07C277/08;C07C279/20;C07C279/22;(IPC1-7):A61K31/19 主分类号 C07D213/65
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