METHOD FOR THE PREPARATION OF TRIACETYLOLEANODOMYCIN

摘要

The method includes acetylation of oleandomycin with aceticanhydride, extraction of the produced product with organic solventand subsequent crystallization from isopropanol. Acetylation ismade in the presence of 2.2-2.5 mol cross-linked copolymer of4-vinylpyridine, divinylbenzene andtrimethylpropanetrimethacrylate of mol oleandomycin recalculatedas pyridine.