| 摘要 |
A biologically active agent (BAA) is based on components of cell membranes (CCM) of homogenized animal tissue which consists of organic substances and has immunomodulating properties. The agent contains modified components of cell membranes with antigen structure modified during the processes of embryogenesis and/or proliferation and/or differentiation of cells, and/or during a pathology preceding or accompanying the process of regeneration and/or repatriation of the tissue. A method for obtaining BAA comprises disintegration and homogenization of a raw material based on animal tissues, subsequent centrifuging and separation of the sediment which contains cell membranes (CM) and of which, after its resuspending, the CCM is obtained. As the raw material modified animal tissues are used whose homogenate is separated from non-disintegrated tissue elements by means of filtration and/or centrifuging at the acceleration of 150-250 g during 10-15 min. and a sediment is separated which contains CM and which is subjected to hydrolysis. The hydrolysis products are filtered or centrifuged at an acceleration exceeding 1500 g during 20-40 min. with separation of supernatant of the hydrolisis products containing BAA as desired product. A pharmaceutical preparation for normalization of physiological state of human beings and animals based on the organic substances. CCM of animal tissues comprises, as active agent, BAA which contains modified CCM in the form of organic substances at the following ratio of components in per cent by weight: peptides 28.0-60.0, amino acids 0.5-31.5, carbonhydrates 16.0-70.0, lipids, nucleotides and other organic substances 0.5-17.0 with the content of BAA in the preparation equal to 0.001-85 % by weight, the balance consisting of a solvent. |
