USE OF MONOCLONAL RECEPTORS TO ONCOPROTEINS FOR MONITORING CANCER THERAPY

摘要

A method of diagnosis e.g. to detect the presence or severity of cancer, involves contacting a body sample e.g. urine, with at least two different receptor molecules to generate a first pattern of reactivity. This pattern may be generated as monoclonal which bind to polypeptides in the sample which are encoded by oncogenes, and is then compared with a second pattern of reactivity generated by a known biological sample. This known sample is indicative of expression of oncogene or oncogene-related sequences. Diagnostic kits utilising this method are also described wherein the results may be interpreted by an automatic scanner.