METHOD FOR PRODUCTION OF 3-ETHYL-5-METHYL-(<EMI ID=0.327 HE=3 WI=3 TI=CHI>)2/(2-AMINOETHOXY)-METHYL-4-(2-CHLOROPHENYL)-1,4- -DIHYDRO-6-METHYL-3,5-PYRIDINE CARBOXYLATE MONOBENZOATE AND INTERMEDIATE FOR THEM

摘要

FIELD: medicine, as antiischemic and antihypertension agent. SUBSTANCE: 3-ethyl-5-methyl-(<EMI ID=0.328 HE=3 WI=3 TI=CHI>)2-/2-(N-triphenylmethylamino)- -ethoxymethyl/-4-2(-chlorophenyl)1,4- dihydro-6-methyl-3,5-pyridine dicarboxylate is used as reagent 1, benzene sulfoacid being used as reagent 2. Reaction is carried out in methanol or in aqueous-methanol medium at temperature from 20 C to boiling point. Melting point of desired compound is 201 C. EFFECT: improved efficiency. 3 clx