The present invention relates to a novel member of the plasminogen activator inhibitor protein family. In particular, isolated nucleic acid molecules are provided encoding the pancreas-derived plasminogen activator inhibitor protein. Pancreas-derived plasminogen activator inhibitor polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to methods for treating physiologic and pathologic disease conditions and diagnostic methods for detecting pathologic disorders.
申请公布号
WO9807735(A1)
申请公布日期
1998.02.26
申请号
WO1996US13283
申请日期
1996.08.16
申请人
HUMAN GENOME SCIENCES, INC.;NI, JIAN;GENTZ, REINER, L.;RUBEN, STEVEN, M.