POLYNUCLEOTIDE VACCINE FORMULA, PARTICULARLY FOR TREATING BOVINE RESPIRATORY DISEASE

摘要

Multivalent polynucleotide vaccine for cattle comprises /- 3 valencies (i.e. it provides protection against /- 3 bovine pathogens), each valency consisting of a plasmid able to express in host cells in vivo /- 1 of the specified antigen genes from one of the following pathogens: (a) bovine herpes virus gB and gD genes; (b) bovine syncytial respiratory virus F and G genes; (c) bovine pest virus E2, C+E1+E2 and E1+E2 genes, and (d) parainfluenza virus type 3 HN and F genes.