New galenic process for omeprazole containing pellets

摘要

A production method for pellets containing Omeprazole performed with an inert core based on sacarose, starch and glucose, said core covered with the micronized and sieved active substance which is in a buffered dispersion, being added with an anionic surface active agent, in order to finally receive an enteric covering in a fluidized bed with HPMC phylate, diethyl phylate, aceton and etheyl alcohol being afterwards dried to obtain a water content of less than 1%, sieved, weigthed and capsulated.